APOL1 G1 genotype modifies the association between HDLC and kidney function in African Americans

BACKGROUND: Despite evidence of an association between variants at the apolipoprotein L1 gene (APOL1) locus and a spectrum of related kidney diseases, underlying biological mechanisms remain unknown. An earlier preliminary study published by our group showed that an APOL1 variant (rs73885319) modifi...

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Pubblicato in:BMC Genomics
Autori principali: Bentley, Amy R., Divers, Jasmin, Shriner, Daniel, Doumatey, Ayo P., Gutiérrez, Orlando M., Adeyemo, Adebowale A., Freedman, Barry I., Rotimi, Charles N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448293/
https://ncbi.nlm.nih.gov/pubmed/26025194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1645-7
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