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Spy1 Protein Mediates Phosphorylation and Degradation of SCG10 Protein in Axonal Degeneration

Axon loss is a destructive consequence of a wide range of neurological diseases without a clearly defined mechanism. Recent data demonstrate that SCG10 is a novel axonal maintenance factor and that rapid SCG10 loss after injury requires JNK activity; how JNK induces degradation of SCG10 is not well...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Liu, Yonghua, Wang, Youhua, Chen, Ying, Li, Xiaohong, Yang, Jiao, Liu, Yang, Shen, Aiguo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447963/
https://ncbi.nlm.nih.gov/pubmed/25869138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.611574
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