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Targeting of folate receptor β on acute myeloid leukemia blasts with chimeric antigen receptor–expressing T cells
T cells expressing a chimeric antigen receptor (CAR) can produce dramatic results in lymphocytic leukemia patients; however, therapeutic strategies for myeloid leukemia remain limited. Folate receptor β (FRβ) is a myeloid-lineage antigen expressed on 70% of acute myeloid leukemia (AML) patient sampl...
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| Veröffentlicht in: | Blood |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4447861/ https://ncbi.nlm.nih.gov/pubmed/25887778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-612721 |
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