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Targeting of folate receptor β on acute myeloid leukemia blasts with chimeric antigen receptor–expressing T cells

T cells expressing a chimeric antigen receptor (CAR) can produce dramatic results in lymphocytic leukemia patients; however, therapeutic strategies for myeloid leukemia remain limited. Folate receptor β (FRβ) is a myeloid-lineage antigen expressed on 70% of acute myeloid leukemia (AML) patient sampl...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Lynn, Rachel C., Poussin, Mathilde, Kalota, Anna, Feng, Yang, Low, Philip S., Dimitrov, Dimiter S., Powell, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447861/
https://ncbi.nlm.nih.gov/pubmed/25887778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-11-612721
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