Innate Susceptibility to Norovirus Infections Influenced by FUT2 Genotype in a United States Pediatric Population

Background. Norovirus is a leading cause of acute gastroenteritis (AGE). Noroviruses bind to gut histo-blood group antigens (HBGAs), but only 70%–80% of individuals have a functional copy of the FUT2 (“secretor”) gene required for gut HBGA expression; these individuals are known as “secretors.” Susc...

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Bibliografski detalji
Izdano u:Clin Infect Dis
Glavni autori: Currier, Rebecca L., Payne, Daniel C., Staat, Mary A., Selvarangan, Rangaraj, Shirley, S. Hannah, Halasa, Natasha, Boom, Julie A., Englund, Janet A., Szilagyi, Peter G., Harrison, Christopher J., Klein, Eileen J., Weinberg, Geoffrey A., Wikswo, Mary E., Parashar, Umesh, Vinjé, Jan, Morrow, Ardythe L.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Articles and Commentaries
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447782/
https://ncbi.nlm.nih.gov/pubmed/25744498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ165
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