Innate Susceptibility to Norovirus Infections Influenced by FUT2 Genotype in a United States Pediatric Population

Background. Norovirus is a leading cause of acute gastroenteritis (AGE). Noroviruses bind to gut histo-blood group antigens (HBGAs), but only 70%–80% of individuals have a functional copy of the FUT2 (“secretor”) gene required for gut HBGA expression; these individuals are known as “secretors.” Susc...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Currier, Rebecca L., Payne, Daniel C., Staat, Mary A., Selvarangan, Rangaraj, Shirley, S. Hannah, Halasa, Natasha, Boom, Julie A., Englund, Janet A., Szilagyi, Peter G., Harrison, Christopher J., Klein, Eileen J., Weinberg, Geoffrey A., Wikswo, Mary E., Parashar, Umesh, Vinjé, Jan, Morrow, Ardythe L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Articles and Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447782/
https://ncbi.nlm.nih.gov/pubmed/25744498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ165
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