Deciphering the Regulatory Logic of an Ancient, Ultraconserved Nuclear Receptor Enhancer Module

Cooperative, synergistic gene regulation by nuclear hormone receptors can increase sensitivity and amplify cellular responses to hormones. We investigated thyroid hormone (TH) and glucocorticoid (GC) synergy on the Krüppel-like factor 9 (Klf9) gene, which codes for a zinc finger transcription factor...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Bagamasbad, Pia D., Bonett, Ronald M., Sachs, Laurent, Buisine, Nicolas, Raj, Samhitha, Knoedler, Joseph R., Kyono, Yasuhiro, Ruan, Yijun, Ruan, Xiaoan, Denver, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447637/
https://ncbi.nlm.nih.gov/pubmed/25866873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1349
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