Deciphering the Regulatory Logic of an Ancient, Ultraconserved Nuclear Receptor Enhancer Module

Cooperative, synergistic gene regulation by nuclear hormone receptors can increase sensitivity and amplify cellular responses to hormones. We investigated thyroid hormone (TH) and glucocorticoid (GC) synergy on the Krüppel-like factor 9 (Klf9) gene, which codes for a zinc finger transcription factor...

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Detalles Bibliográficos
Publicado en:Mol Endocrinol
Autores principales: Bagamasbad, Pia D., Bonett, Ronald M., Sachs, Laurent, Buisine, Nicolas, Raj, Samhitha, Knoedler, Joseph R., Kyono, Yasuhiro, Ruan, Yijun, Ruan, Xiaoan, Denver, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2015
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447637/
https://ncbi.nlm.nih.gov/pubmed/25866873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1349
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