Chitosan Enriched Three-Dimensional Matrix Reduces Inflammatory and Catabolic Mediators Production by Human Chondrocytes

This in vitro study investigated the metabolism of human osteoarthritic (OA) chondrocytes encapsulated in a spherical matrix enriched of chitosan. Human OA chondrocytes were encapsulated and cultured for 28 days either in chitosan-alginate beads or in alginate beads. The beads were formed by slowly...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Oprenyeszk, Frederic, Sanchez, Christelle, Dubuc, Jean-Emile, Maquet, Véronique, Henrist, Catherine, Compère, Philippe, Henrotin, Yves
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447380/
https://ncbi.nlm.nih.gov/pubmed/26020773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128362
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