Quantitative Measurement of GPCR Endocytosis via Pulse-Chase Covalent Labeling

G protein-coupled receptors (GPCRs) play a critical role in many physiological systems and represent one of the largest families of signal-transducing receptors. The number of GPCRs at the cell surface regulates cellular responsiveness to their cognate ligands, and the number of GPCRs, in turn, is d...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kumagai, Hidetoshi, Ikeda, Yuichi, Motozawa, Yoshihiro, Fujishiro, Mitsuhiro, Okamura, Tomohisa, Fujio, Keishi, Okazaki, Hiroaki, Nomura, Seitaro, Takeda, Norifumi, Harada, Mutsuo, Toko, Haruhiro, Takimoto, Eiki, Akazawa, Hiroshi, Morita, Hiroyuki, Suzuki, Jun-ichi, Yamazaki, Tsutomu, Yamamoto, Kazuhiko, Komuro, Issei, Yanagisawa, Masashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447269/
https://ncbi.nlm.nih.gov/pubmed/26020647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129394
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