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Identification and Characterization of the Binding Sites of P-Glycoprotein for Multidrug Resistance-Related Drugs and Modulators

A major problem in cancer treatment is the development of resistance to multiple chemotherapeutic agents in tumor cells. A major mechanism of this multidrug resistance (MDR) is overexpression of the MDR1 product P-glycoprotein, known to bind to and transport a wide variety of agents. This review con...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Curr Med Chem Anticancer Agents
Päätekijä: Safa, Ahmad R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447203/
https://ncbi.nlm.nih.gov/pubmed/14754408
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