Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

Active neurons exert a mitogenic effect on normal neural precursor and oligodendroglial precursor cells, the putative cellular origins of high-grade glioma (HGG). By using optogenetic control of cortical neuronal activity in a patient-derived pediatric glioblastoma xenograft model, we demonstrate th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Venkatesh, Humsa S., Johung, Tessa B., Caretti, Viola, Noll, Alyssa, Tang, Yujie, Nagaraja, Surya, Gibson, Erin M., Mount, Christopher W., Polepalli, Jai, Mitra, Siddhartha S., Woo, Pamelyn J., Malenka, Robert C., Vogel, Hannes, Bredel, Markus, Mallick, Parag, Monje, Michelle
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447122/
https://ncbi.nlm.nih.gov/pubmed/25913192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.04.012
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