Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

Active neurons exert a mitogenic effect on normal neural precursor and oligodendroglial precursor cells, the putative cellular origins of high-grade glioma (HGG). By using optogenetic control of cortical neuronal activity in a patient-derived pediatric glioblastoma xenograft model, we demonstrate th...

詳細記述

保存先:
書誌詳細
出版年:Cell
主要な著者: Venkatesh, Humsa S., Johung, Tessa B., Caretti, Viola, Noll, Alyssa, Tang, Yujie, Nagaraja, Surya, Gibson, Erin M., Mount, Christopher W., Polepalli, Jai, Mitra, Siddhartha S., Woo, Pamelyn J., Malenka, Robert C., Vogel, Hannes, Bredel, Markus, Mallick, Parag, Monje, Michelle
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447122/
https://ncbi.nlm.nih.gov/pubmed/25913192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.04.012
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