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Synthesis of Vaccinia Virus Polypeptides in the Presence of Hydroxyurea

Hydroxyurea (5 × 10(−3) M) inhibits the development of vaccinia virus in HeLa cells early after infection and prevents the synthesis of viral deoxyribonucleic acid. In the presence of hydroxyurea, late viral polypeptides are not formed, as observed by electrophoresis on polyacrylamide gels. IMAGES:

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Katz, Ehud, Margalith, Eva, Winer, Bela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15825321/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.6.5.647
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