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Synthesis of Vaccinia Virus Polypeptides in the Presence of Hydroxyurea

Hydroxyurea (5 × 10(−3) M) inhibits the development of vaccinia virus in HeLa cells early after infection and prevents the synthesis of viral deoxyribonucleic acid. In the presence of hydroxyurea, late viral polypeptides are not formed, as observed by electrophoresis on polyacrylamide gels. IMAGES:

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Katz, Ehud, Margalith, Eva, Winer, Bela
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1974
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15825321/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.6.5.647
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