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The Maze of APP Processing in Alzheimer’s Disease: Where Did We Go Wrong in Reasoning?

Why has Alzheimer’s disease (AD) remained a conundrum today? The main reason is the stagnation in understanding the origins of plaques and tangles. While they are widely thought to be the products of the “aberrant” pathways, we believe that plaques and tangles result from natural aging. From this ne...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Autor principal: Chen, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447002/
https://ncbi.nlm.nih.gov/pubmed/26052267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00186
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