AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation

Lipid droplets (LDs) are intracellular organelles that provide fatty acids (FAs) to cellular processes including synthesis of membranes and production of metabolic energy. While known to move bidirectionally along microtubules (MTs), the role of LD motion and whether it facilitates interaction with...

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Udgivet i:Nat Commun
Main Authors: Herms, Albert, Bosch, Marta, Reddy, Babu J.N., Schieber, Nicole L., Fajardo, Alba, Rupérez, Celia, Fernández-Vidal, Andrea, Ferguson, Charles, Rentero, Carles, Tebar, Francesc, Enrich, Carlos, Parton, Robert G., Gross, Steven P., Pol, Albert
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446796/
https://ncbi.nlm.nih.gov/pubmed/26013497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8176
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