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Dihydrofolate Reductase in Pediococcus cerevisiae Strains Susceptible and Resistant to Amethopterin
A mutant strain of Pediococcus cerevisiae was obtained which had 1,000-fold greater resistance to amethopterin than the P. cerevisiae/PteGlu strain. The dihydrofolate reductase level of the mutant was about 60-fold higher than that of the parent. The mutant accumulated folate, though less efficientl...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1974
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC444653/ https://ncbi.nlm.nih.gov/pubmed/15830489 |
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