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Dihydrofolate Reductase in Pediococcus cerevisiae Strains Susceptible and Resistant to Amethopterin

A mutant strain of Pediococcus cerevisiae was obtained which had 1,000-fold greater resistance to amethopterin than the P. cerevisiae/PteGlu strain. The dihydrofolate reductase level of the mutant was about 60-fold higher than that of the parent. The mutant accumulated folate, though less efficientl...

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Autors principals: Mandelbaum-Shavit, Frederika, Grossowicz, Nathan
Format: Artigo
Idioma:Inglês
Publicat: 1974
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC444653/
https://ncbi.nlm.nih.gov/pubmed/15830489
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