MDC1 functionally identified as an androgen receptor co-activator participates in suppression of prostate cancer

Mediator of DNA damage checkpoint protein 1 (MDC1) is essential for DNA damage response. However, the role of MDC1 in modulating gene transcription independently of DNA damage and the underlying mechanisms have not been fully defined. Androgen receptor (AR) is the central signaling pathway in prosta...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Wang, Chunyu, Sun, Hongmiao, Zou, Renlong, Zhou, Tingting, Wang, Shengli, Sun, Shiying, Tong, Changci, Luo, Hao, Li, Yanshu, Li, Zhenhua, Wang, Enhua, Chen, Yuhua, Cao, Liu, Li, Feng, Zhao, Yue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446443/
https://ncbi.nlm.nih.gov/pubmed/25934801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv394
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