Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4.

Leukotriene (LT) C4 synthase, an integral microsomal membrane protein, conjugates LTA4, an epoxide intermediate, to reduced glutathione (GSH) to form a proinflammatory mediator, LTC4. A sensitive fluorescence-linked immunoassay for LTC4 was used to screen a KG-1 cDNA expression library for LTC4 synt...

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Detaylı Bibliyografya

Yayımlandı:	Proc Natl Acad Sci U S A
Asıl Yazarlar:	Lam, B K, Penrose, J F, Freeman, G J, Austen, K F
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	National Academy of Sciences 1994
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7663
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