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Rh-Catalyzed C–C Bond Cleavage by Transfer Hydroformylation

The dehydroformylation of aldehydes to generate olefins occurs during the biosynthesis of various sterols, including cholesterol in humans. Here, we implement a synthetic version that features the transfer of a formyl group and hydride from an aldehyde substrate to a strained olefin acceptor. A Rh(X...

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Pubblicato in:Science
Autori principali: Murphy, Stephen K., Park, Jung-Woo, Cruz, Faben A., Dong, Vy M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445961/
https://ncbi.nlm.nih.gov/pubmed/25554782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1261232
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