Protein synthesis elongation factor EF-1 alpha is essential for ubiquitin-dependent degradation of certain N alpha-acetylated proteins and may be substituted for by the bacterial elongation factor EF-Tu.

Targeting of different cellular proteins for conjugation and subsequent degradation via the ubiquitin pathway involves diverse recognition signals and distinct enzymatic factors. A few proteins are recognized via their N-terminal amino acid residue and conjugated by a ubiquitin-protein ligase that r...

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Библиографические подробности
Главные авторы: Gonen, H, Smith, C E, Siegel, N R, Kahana, C, Merrick, W C, Chakraburtty, K, Schwartz, A L, Ciechanover, A
Формат: Artigo
Язык:Inglês
Опубликовано: 1994
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC44459/
https://ncbi.nlm.nih.gov/pubmed/8052636
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