A role for D-aspartate oxidase in schizophrenia and in schizophrenia-related symptoms induced by phencyclidine in mice

Increasing evidence points to a role for dysfunctional glutamate N-methyl-D-aspartate receptor (NMDAR) neurotransmission in schizophrenia. D-aspartate is an atypical amino acid that activates NMDARs through binding to the glutamate site on GluN2 subunits. D-aspartate is present in high amounts in th...

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Vydáno v:Transl Psychiatry
Hlavní autoři: Errico, F, D'Argenio, V, Sforazzini, F, Iasevoli, F, Squillace, M, Guerri, G, Napolitano, F, Angrisano, T, Di Maio, A, Keller, S, Vitucci, D, Galbusera, A, Chiariotti, L, Bertolino, A, de Bartolomeis, A, Salvatore, F, Gozzi, A, Usiello, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445752/
https://ncbi.nlm.nih.gov/pubmed/25689573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.2
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