Free D-aspartate regulates neuronal dendritic morphology, synaptic plasticity, gray matter volume and brain activity in mammals

D-aspartate (D-Asp) is an atypical amino acid, which is especially abundant in the developing mammalian brain, and can bind to and activate N-methyl-D-Aspartate receptors (NMDARs). In line with its pharmacological features, we find that mice chronically treated with D-Asp show enhanced NMDAR-mediate...

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Detalhes bibliográficos
Main Authors: Errico, F, Nisticò, R, Di Giorgio, A, Squillace, M, Vitucci, D, Galbusera, A, Piccinin, S, Mango, D, Fazio, L, Middei, S, Trizio, S, Mercuri, N B, Teule, M A, Centonze, D, Gozzi, A, Blasi, G, Bertolino, A, Usiello, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119226/
https://ncbi.nlm.nih.gov/pubmed/25072322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2014.59
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