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Antiviral Activity of Cytarabine in Herpesvirus–Infected Rats
Intranasal inoculation of herpesvirus (approximately 1.8 mean lethal doses [LD(50)] in 0.1 ml) into 105- to 115-g rats produces paralytic disease in 4 to 5 days and 80 to 100% mortality in 8 to 12 days. Cytarabine (ara-C) (40 to 320 mg/kg), administered subcutaneously to inoculated rats, delays the...
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| Publicado no: | Antimicrob Agents Chemother |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1973
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444574/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4364763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.4.4.439 |
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