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Antiviral Activity of Cytarabine in Herpesvirus–Infected Rats
Intranasal inoculation of herpesvirus (approximately 1.8 mean lethal doses [LD(50)] in 0.1 ml) into 105- to 115-g rats produces paralytic disease in 4 to 5 days and 80 to 100% mortality in 8 to 12 days. Cytarabine (ara-C) (40 to 320 mg/kg), administered subcutaneously to inoculated rats, delays the...
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| Vydáno v: | Antimicrob Agents Chemother |
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| Hlavní autor: | |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1973
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444574/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4364763/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.4.4.439 |
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