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Antiangiogenic Variant of TSP-1 Targets Tumor Cells in Glioblastomas

Three type-1 repeat (3TSR) domain of thrombospondin-1 is known to have anti-angiogenic effects by targeting tumor-associated endothelial cells, but its effect on tumor cells is unknown. This study explored the potential of 3TSR to target glioblastoma (GBM) cells in vitro and in vivo. We show that 3T...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther
Prif Awduron: Choi, Sung Hugh, Tamura, Kaoru, Khajuria, Rajiv Kumar, Bhere, Deepak, Nesterenko, Irina, Lawler, Jack, Shah, Khalid
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445617/
https://ncbi.nlm.nih.gov/pubmed/25358253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.214
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