Expression of O(6)-methylguanine-DNA methyltransferase causes lomustine resistance in canine lymphoma cells

The DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT) causes resistance to nitrosoureas in various human cancers. In this study, we analyzed the correlation between canine lymphomas and MGMT in vitro. Two of five canine lymphoma cell lines required higher concentrations of lomustine...

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Detalhes bibliográficos
Publicado no:Can J Vet Res
Main Authors: Kambayashi, Satoshi, Minami, Kouji, Ogawa, Yuka, Hamaji, Takehiro, Hwang, Chung Chew, Igase, Masaya, Hiraoka, Hiroko, Miyama, Takako Shimokawa, Noguchi, Shunsuke, Baba, Kenji, Mizuno, Takuya, Okuda, Masaru
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Veterinary Medical Association 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445512/
https://ncbi.nlm.nih.gov/pubmed/26130852
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