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Expression of O(6)-methylguanine-DNA methyltransferase causes lomustine resistance in canine lymphoma cells
The DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT) causes resistance to nitrosoureas in various human cancers. In this study, we analyzed the correlation between canine lymphomas and MGMT in vitro. Two of five canine lymphoma cell lines required higher concentrations of lomustine...
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| Veröffentlicht in: | Can J Vet Res |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Canadian Veterinary Medical Association
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4445512/ https://ncbi.nlm.nih.gov/pubmed/26130852 |
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