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Bispecific T cell engagers for cancer immunotherapy

Bispecific T cell engagers are a new class of immunotherapeutic molecules intended for the treatment of cancer. These molecules, termed BiTEs, enhance the patient’s immune response to tumors by retargeting T cells to tumor cells. BiTEs are constructed of two single chain variable fragments (scFv) co...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Huehls, Amelia M., Coupet, Tiffany A., Sentman, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445461/
https://ncbi.nlm.nih.gov/pubmed/25367186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2014.93
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