PIK3CA Amplification Is Common in Left Side-Tubular Adenomas but Uncommon Sessile Serrated Adenomas Exclusively with KRAS Mutation

Colorectal cancer is a heterogeneous disorder than arises via multiple distinct pathways, from tubular adenomas (TAs) and sessile serrated adenomas (SSAs), which are clinically, morphologically, and molecularly different. We examined PIK3CA amplification in colorectal precancerous legions, including...

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Pubblicato in:Int J Med Sci
Autori principali: Lee, Hyunsu, Lee, Jae-Ho, Kim, Dae-Kwang, Choi, In-Jang, Hwang, Ilseon, Kang, Yu-Na, Kim, Shin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445015/
https://ncbi.nlm.nih.gov/pubmed/26019684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.11281
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