5-Fluorocytosine Resistance in Cryptococcus neoformans

Isolates of Cryptococcus neoformans from six patients were obtained before and after unsuccessful therapy with 5-fluorocytosine (5-FC). Post-therapy isolates exhibited massive and stable 5-FC resistance. The frequency of drug-resistant mutants in susceptible isolates of C. neoformans was <0.001%...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Block, Edward R., Jennings, Anne E., Bennett, John E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1973
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4597734/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.3.6.649
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