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5-Fluorocytosine Resistance in Cryptococcus neoformans

Isolates of Cryptococcus neoformans from six patients were obtained before and after unsuccessful therapy with 5-fluorocytosine (5-FC). Post-therapy isolates exhibited massive and stable 5-FC resistance. The frequency of drug-resistant mutants in susceptible isolates of C. neoformans was <0.001%...

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Detalhes bibliográficos
Main Authors: Block, Edward R., Jennings, Anne E., Bennett, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444474/
https://ncbi.nlm.nih.gov/pubmed/4597734
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