Modifications of azoxymethane-induced carcinogenesis and 90-day oral toxicities of 2-tetradecylcyclobutanone as a radiolytic product of stearic acid in F344 rats

A 90-day oral toxicity test in rats was performed to evaluate the toxicity of 2-tetradecylcyclobutanone (2-tDCB), a unique radiolytic product of stearic acid. Six-week-old male and female F344 rats (n=15/group) were given 2-tDCB at concentrations of 0, 12, 60 and 300 ppm in a powder diet for 13 week...

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Detalhes bibliográficos
Publicado no:J Toxicol Pathol
Main Authors: Sato, Makoto, Todoriki, Setsuko, Takahashi, Tetsuyuki, Hafez, Ezar, Takasu, Chie, Uehara, Hisanori, Yamakage, Kohji, Kondo, Takashi, Matsumoto, Kozo, Furuta, Masakazu, Izumi, Keisuke
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Society of Toxicologic Pathology 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444508/
https://ncbi.nlm.nih.gov/pubmed/26028819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2015-0002
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