High Susceptibility to Zymbal Gland and Intestinal Carcinogenesis in Diabetic Otsuka Long-Evans Tokushima Fatty Rats

Diabetes mellitus (DM) and obesity are believed to be risk factors for colorectal cancer in humans. In experiment 1, male nondiabetic Long-Evans Tokushima Otsuka (LETO) rats and Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model animal of type 2 DM, were whole-body X-irradiated (4 Gy) at 6 and...

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Main Authors: Hafez, Ezar, Takahashi, Tetsuyuki, Ogawa, Hirohisa, Sato, Makoto, Nakai, Tokiko, Takasu, Chie, Uehara, Hisanori, Izumi, Keisuke
Format: Artigo
Jezik:Inglês
Izdano: The Japanese Society of Toxicologic Pathology 2011
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Original
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266353/
https://ncbi.nlm.nih.gov/pubmed/22319230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.24.187
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