Oxidation of the aromatic amino acids tryptophan and tyrosine disrupts their anabolic effects on bone marrow mesenchymal stem cells

Age-induced bone loss is associated with greater bone resorption and decreased bone formation resulting in osteoporosis and osteoporosis-related fractures. The etiology of this age-induced bone loss is not clear but has been associated with increased generation of reactive oxygen species (ROS) from...

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Detalhes bibliográficos
Publicado no:Mol Cell Endocrinol
Main Authors: Refaey, Mona El, Watkins, Christopher P., Kennedy, Eileen, Chang, Andrew, Zhong, Qing, Ding, Ke-Hong, Shi, Xing-ming, Xu, Jianrui, Bollag, Wendy B., Hill, William D., Johnson, Maribeth, Hunter, Monte, Hamrick, Mark W, Isales, Carlos M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444384/
https://ncbi.nlm.nih.gov/pubmed/25637715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.01.034
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