1-Methyl-4-Phenylpyridinium Stereotactic Infusion Completely and Specifically Ablated the Nigrostriatal Dopaminergic Pathway in Rhesus Macaque

INTRODUCTION: Complete and specific ablation of a single dopaminergic (DA) pathway is a critical step to distinguish the roles of DA pathways in vivo. However, this kind of technique has not been reported in non-human primates. This study aimed to establish a lesioning method with a complete and spe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lei, Xiaoguang, Li, Hao, Huang, Baihui, Rizak, Joshua, Li, Ling, Xu, Liqi, Liu, Li, Wu, Jing, Lü, Longbao, Wang, Zhengbo, Hu, Yingzhou, Le, Weidong, Deng, Xingli, Li, Jiali, Yao, Yonggang, Xu, Lin, Hu, Xintian, Zhang, Baorong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444358/
https://ncbi.nlm.nih.gov/pubmed/26010745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127953
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