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Estrogen Receptor β2 Induces Hypoxia Signature of Gene Expression by Stabilizing HIF-1α in Prostate Cancer

The estrogen receptor (ER) β variant ERβ2 is expressed in aggressive castration-resistant prostate cancer and has been shown to correlate with decreased overall survival. Genome-wide expression analysis after ERβ2 expression in prostate cancer cells revealed that hypoxia was an overrepresented theme...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dey, Prasenjit, Velazquez-Villegas, Laura A., Faria, Michelle, Turner, Anthony, Jonsson, Philp, Webb, Paul, Williams, Cecilia, Gustafsson, Jan-Åke, Ström, Anders M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444278/
https://ncbi.nlm.nih.gov/pubmed/26010887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128239
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