Estrogen Receptors β1 and β2 Have Opposing Roles in Regulating Proliferation and Bone Metastasis Genes in the Prostate Cancer Cell Line PC3

The estrogen receptor (ER)β1 is successively lost during cancer progression, whereas its splice variant, ERβ2, is expressed in advanced prostate cancer. The latter form of cancer often metastasizes to bone, and we wanted to investigate whether the loss of ERβ1 and/or the expression of ERβ2 affect su...

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Detalhes bibliográficos
Main Authors: Dey, Prasenjit, Jonsson, Philip, Hartman, Johan, Williams, Cecilia, Ström, Anders, Gustafsson, Jan-Åke
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517717/
https://ncbi.nlm.nih.gov/pubmed/23028063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012.1227
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