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Comprehensive Assessment of Genetic Sequence Variants in the Antioxidant ‘Master Regulator’ Nrf2 in Idiopathic Parkinson’s Disease

Parkinson’s disease (PD) is a complex neurodegenerative disorder influenced by a combination of genetic and environmental factors. The molecular mechanisms that underlie PD are unknown; however, oxidative stress and impairment of antioxidant defence mechanisms have been implicated as major contribut...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Todorovic, Michael, Newman, Jeremy R. B., Shan, Jianguo, Bentley, Steven, Wood, Stephen A., Silburn, Peter A., Mellick, George D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444110/
https://ncbi.nlm.nih.gov/pubmed/26010367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128030
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