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Reversible Inhibition of Herpes Simplex Virus Replication by Hydroxyurea

Hydroxyurea, at a concentration of 5 × 10(−2) M, inhibits the replication of herpes simplex deoxyribonucleic acid (DNA) in the nuclei of infected cells. As a result, the synthesis of infectious virus progeny was prevented. The presence of parental viral DNA genomes in inhibited cells led to the synt...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Rosenkranz, Herbert S., Becker, Yechiel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444409/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4364174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.3.3.325
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