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Reversible Inhibition of Herpes Simplex Virus Replication by Hydroxyurea

Hydroxyurea, at a concentration of 5 × 10(−2) M, inhibits the replication of herpes simplex deoxyribonucleic acid (DNA) in the nuclei of infected cells. As a result, the synthesis of infectious virus progeny was prevented. The presence of parental viral DNA genomes in inhibited cells led to the synt...

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Autors principals: Rosenkranz, Herbert S., Becker, Yechiel
Format: Artigo
Idioma:Inglês
Publicat: 1973
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC444409/
https://ncbi.nlm.nih.gov/pubmed/4364174
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