Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients

UDP-glucuronosyltransferases (UGTs), the most important enzymes in body detoxification and homeostasis maintaining, govern the glucuronidation reaction of various endogenous and environmental carcinogens. The metabolic function of UGTs can be severely influenced by hepatocellular carcinoma (HCC), th...

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Publicado en:PLoS One
Main Authors: Lu, Linlin, Zhou, Juan, Shi, Jian, Peng, Xiao-juan, Qi, Xiao-xiao, Wang, Ying, Li, Fang-yuan, Zhou, Fu-Yuan, Liu, Liang, Liu, Zhong-Qiu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444081/
https://ncbi.nlm.nih.gov/pubmed/26010150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127524
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