A Function for the hnRNP A1/A2 Proteins in Transcription Elongation

The hnRNP A1 and A2 proteins regulate processes such as alternative pre-mRNA splicing and mRNA stability. Here, we report that a reduction in the levels of hnRNP A1 and A2 by RNA interference or their cytoplasmic retention by osmotic stress drastically increases the transcription of a reporter gene....

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Udgivet i:PLoS One
Main Authors: Lemieux, Bruno, Blanchette, Marco, Monette, Anne, Mouland, Andrew J., Wellinger, Raymund J., Chabot, Benoit
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444011/
https://ncbi.nlm.nih.gov/pubmed/26011126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126654
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