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Diphtheria toxin treatment of Pet-1-Cre floxed diphtheria toxin receptor mice disrupts thermoregulation without affecting respiratory chemoreception

In genetically-modified Lmx1b(f/f/p) mice, selective deletion of LMX1B in Pet-1 expressing cells leads to failure of embryonic development of serotonin (5-HT) neurons. As adults, these mice have a decreased hypercapnic ventilatory response and abnormal thermoregulation. This mouse model has been val...

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Foilsithe in:Neuroscience
Main Authors: Cerpa, Verónica, Gonzalez, Amalia, Richerson, George B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443915/
https://ncbi.nlm.nih.gov/pubmed/25171790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.08.018
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