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Comparison of the effects of moderate and severe hypercapnic acidosis on ventilation-induced lung injury

BACKGROUND: We have proved that hypercapnic acidosis (a PaCO(2) of 80-100 mmHg) protects against ventilator-induced lung injury in rats. However, there remains uncertainty regarding the appropriate target PaCO(2) or if greater CO(2) “doses” (PaCO(2) > 100 mmHg) demonstrate this effect. We wished...

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Detalhes bibliográficos
Publicado no:BMC Anesthesiol
Main Authors: Yang, Wanchao, Yue, Ziyong, Cui, Xiaoguang, Guo, Yueping, Zhang, Lili, Zhou, Huacheng, Li, Wenzhi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443663/
https://ncbi.nlm.nih.gov/pubmed/25924944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-015-0050-8
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