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Impact of buffering hypercapnic acidosis on cell wounding in ventilator-injured rat lungs

We measured the effects of raising perfusate pH on ventilator-induced cell wounding and repair in ex vivo mechanically ventilated hypercapnic rat lungs. Lungs were randomized to one of three perfusate groups: 1) unbuffered hypercapnic acidosis, 2) bicarbonate-buffered hypercapnia, or 3) tris-hydroxy...

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Main Authors: Caples, Sean M., Rasmussen, Deborah L., Lee, Won Y., Wolfert, Marla Z., Hubmayr, Rolf D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636949/
https://ncbi.nlm.nih.gov/pubmed/18996901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90339.2008
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