RNA-seq identifies a role for the PPARβ/δ inverse agonist GSK0660 in the regulation of TNFα-induced cytokine signaling in retinal endothelial cells

PURPOSE: The peroxisome proliferator-activated receptor beta/delta (PPARβ/δ) is a transcription factor with roles in metabolism, angiogenesis, and inflammation. It has yet undefined roles in retinal inflammation and diabetic retinopathy (DR). We used RNA-seq to better understand the role of the anta...

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Bibliografske podrobnosti
izdano v:Mol Vis
Main Authors: Savage, Sara R., McCollum, Gary W., Yang, Rong, Penn, John S.
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443583/
https://ncbi.nlm.nih.gov/pubmed/26015769
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