Tobacco smoking is associated with methylation of genes related to coronary artery disease

BACKGROUND: Tobacco smoking, a risk factor for coronary artery disease (CAD), is known to modify DNA methylation. We hypothesized that tobacco smoking modifies methylation of the genes identified for CAD by genome-wide association study (GWAS). RESULTS: We selected genomic regions based on 150 singl...

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Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Steenaard, Rebecca V, Ligthart, Symen, Stolk, Lisette, Peters, Marjolein J, van Meurs, Joyce B, Uitterlinden, Andre G, Hofman, Albert, Franco, Oscar H, Dehghan, Abbas
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443552/
https://ncbi.nlm.nih.gov/pubmed/26015811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0088-y
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