Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes

AIMS/HYPOTHESIS: Tobacco smoking, a risk factor for diabetes, is an established modifier of DNA methylation. We hypothesised that tobacco smoking modifies DNA methylation of genes previously identified for diabetes. METHODS: We annotated CpG sites available on the Illumina Human Methylation 450K arr...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Ligthart, Symen, Steenaard, Rebecca V., Peters, Marjolein J., van Meurs, Joyce B. J., Sijbrands, Eric J. G., Uitterlinden, André G., Bonder, Marc J., Hofman, Albert, Franco, Oscar H., Dehghan, Abbas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826423/
https://ncbi.nlm.nih.gov/pubmed/26825526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-3872-0
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