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Mast cell-derived IL-1β contributes to uric acid crystal-induced acute arthritis in mice

OBJECTIVE: Gouty arthritis is caused by precipitation in joints of crystals of monosodium urate (MSU). While it has been reported that mast cells (MCs) infiltrate gouty tophi, little is known about the actual roles of MCs during acute attacks of gout. This study was undertaken to assess the role of...

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Dettagli Bibliografici
Pubblicato in:Arthritis Rheumatol
Autori principali: Reber, Laurent L, Marichal, Thomas, Sokolove, Jeremy, Starkl, Philipp, Gaudenzio, Nicolas, Iwakura, Yoichiro, Karasuyama, Hajime, Schwartz, Lawrence B, Robinson, William H, Tsai, Mindy, Galli, Stephen J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443497/
https://ncbi.nlm.nih.gov/pubmed/24943488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38747
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